ea0022p481 | Female reproduction | ECE2010
Diamanti-Kandarakis Evanthia
, Livadas Sarantis
, Katsikis Ilias
, Piperi Christine
, Mantziou Aimilia
, Papavassiliou Athanasios G
, Panidis Dimitrios
Objective: Intriguing studies suggest that osteocalcin (OC) and its carboxylated (Gla)/uncarboxylated form are involved in the regulation of insulin secretion and action. Additionally, advanced glycated end products (AGEs), directly regulate the secretion of these osteoblast derived molecules. In PCOS among the pathophysiological aberrations, deregulation of insulin secretion and action as well as elevated AGEs levels have been demonstrated. In this study, we evaluated the ser...